"Whoever isolates himself seeks his own desire; he breaks out against all sound judgment."Sin motivates us away from relationships; when Adam and Eve sinned, they hid.
If aggressive personalities were to confront one about depression the potential for increased conflict is inherent the individual addressing the depressive person, must come with confidence of character and strong personality, being able to handle any rebuttal which might arise, offering a forgiving and compassionate answer to the emotional well which might erupt from this persons heart.
If your desire to confront the person is of a pure heart, acknowledging the depravity of this persons flesh is necessary and forgiving the origin and acknowledging the division between their true character as a Christian and the foothold sin has taken. When you choose to confront the sensitive area, which has been denied and protected for so long, it is like doing surgery. You must expect some very violent responses when you begin to cut into a sin infected facet of this persons soul. For they have built no tolerance to deal with it for it has always been a protected area and has no category to understand the eventual positive fruit of receiving such excruciating criticism as pain. Ultimately we must realize that the flaw of sin rests with the individual. Accordingly it is the goal of this person to transcend the situation and find their purpose within this context, avoiding the obvious potential to nihilistically approach the situation, focusing on their own emotions evoked and lack of interests entertained.